Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 3
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Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 3 Descriptor: (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide, ACETIC ACID, Dihydroorotate dehydrogenase, ... Authors: Heikkila, T. Deposit date: 2008-12-14 Release date: 2009-06-09 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases J.Med.Chem., 52, 2009
创建时间:
2008-12-14



