Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.
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https://www.ncbi.nlm.nih.gov/sra/SRP225109
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资源简介:
Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated reduction of mTORC1 signaling, aerobic respiration and expression of genes involved in ribosome biogenesis. Overall design: RNAseq analysis of transitional and follicular B cells from healthy human donors and C57BL/6 (wild-type) mice
创建时间:
2025-07-23



