Structure of compound 5c-S bound at the active site of COX-2
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Structure of compound 5c-S bound at the active site of COX-2 Descriptor: (2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Kiefer, J.R, Kurumbail, R.G, Stallings, W.C, Pawlitz, J.L. Deposit date: 2010-02-01 Release date: 2010-10-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life. Bioorg.Med.Chem.Lett., 20, 2010
创建时间:
2010-02-01



