Mouse models have been developed to investigate colorectal cancer etiology and evaluate new anti-cancer therapies. While genetically engineered and carcinogen-induced mouse models have provided impor

NIAID Data Ecosystem50

Oncogenic KRAS in a CRC mouse model with conditional null alleles of Apc and Trp53 tumor suppressors

结直肠癌模型

基因功能研究

A genetically engineered mouse model of metastatic colorectal cancer harboring an inducible oncogenic Kras allele (Krasmut) and conditional null alleles of Apc and Trp53 tumor suppressors was generate

NIAID Data Ecosystem40

Effect of PGE2 pathway antagonists on APCmin/+ small intestine polyps

结直肠癌模型

前列腺素信号通路靶向治疗

While the role of prostaglandin E2 (PGE2) in promoting malignant progression is well-established, how to optimally block the activity of PGE2 signaling remains to be demonstrated. Clinical trials with

NIAID Data Ecosystem20

Molecular Evaluation of Patient-Derived Colorectal Cancer Explants as a Pre-clinical Mouse Model of Colorectal Cancer

资源简介：

Molecular Evaluation of Patient-Derived Colorectal Cancer Explants as a Pre-clinical Mouse Model of Colorectal Cancer

资源简介：

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