Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-259
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Crystal structure of the first bromodomain (BD1) of human BRD4 bound to NC-II-259 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide Authors: Chan, A, Schonbrunn, E. Deposit date: 2021-05-07 Release date: 2022-08-03 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.16 Å) Cite: Bivalent BET Bromodomain Inhibitors Confer Increased Potency and Selectivity for BRDT via Protein Conformational Plasticity. J.Med.Chem., 65, 2022
创建时间：
2021-05-07
