Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of γ‑Lactones, Isobenzofuranones, and Tetrahydrofurans
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https://figshare.com/articles/dataset/Alkene_Dioxygenation_with_Malonoyl_Peroxides_Synthesis_of_Lactones_Isobenzofuranones_and_Tetrahydrofurans/3443174
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资源简介：
Treatment of homoallylic alcohols or carboxylic acids with malonoyl peroxide 1 provides a stereoselective method for the preparation of tetrahydrofurans, γ-lactones, and isobenzofuranones in 44–82% yield and up to 27:1 trans selectivity. Application of this simple and effective heterocyclization in the synthesis of the antidepressant citalopram is also described.
创建时间：
2016-06-27
