Crystal structure of YTHDC1 in complex with YL-5092

Crystal structure of YTHDC1 in complex with YL-5092 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-[4-(1,3-thiazol-5-yl)phenyl]-4-[2-(trifluoromethyl)phenyl]carbonyl-1H-pyrrole-2-carboxamide, SULFATE ION, ... Authors: Zhang, H, Yang, S. Deposit date: 2025-03-15 Release date: 2025-12-24 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Small-molecule inhibition of YTHDC1 as a strategy against acute myeloid leukemia in mouse models. Sci Transl Med, 18, 2026