In vitro evaluation of the concentration of fluoride released by pediatric toothpastes sold in the Dominican market

Dental caries is among the most prevalent oral diseases in children, and its prevention is
intimately associated with the utilization of fluoridated toothpastes. However, an inadequate
concentration of fluoride, whether in excess or deficiency, can compromise the product's
efficacy and safety as a preventative measure. The present study evaluated the fluoride
concentration of three pediatric toothpastes available on the Dominican market (Colgate
Smiles, Oral B Kids, and Oddent Flúor Infantil) in vitro, with the objective of verifying the
compliance of these products with the manufacturer's claims and the limits established by
health regulations.
A total of 75 samples (25 samples per brand) were subjected to analysis using the ion-
selective electrode method, a technique that has been recognized for its accuracy in
determining free fluoride concentrations. The procedure entailed the calibration of the
instrument with standard solutions, the implementation of pH control utilizing TISAB III
solution, and the execution of potentiometric measurement employing Mettler-Toledo
equipment. The results obtained were expressed in ppm and subjected to statistical analysis.
The findings indicated that Colgate Smiles contained a higher concentration of fluoride than
indicated on its packaging, without compromising its preventive efficacy, while Oral B Kids
had a slightly lower concentration but within acceptable ranges (500–1450 ppm). Conversely,
Oddent Flúor Infantil exhibited levels that fell below the recommended minimum (377 ppm), a
circumstance that has the potential to compromise its anticariogenic effectiveness. These
variations underscore discrepancies between the stated and the contained, and they highlight
the necessity for enhanced regulation and quality control measures in children's dental

products.
It is concluded that, although some brands comply with the established parameters, others
could represent a limitation in protection against caries. This information is of particular value
to oral health professionals when formulating recommendations for safe and effective
products. Furthermore, it underscores the necessity of independent research to validate the
actual content of products available on the local market.