Single Cell Transcriptomic Analysis in a Mouse Model of Barth Syndrome Reveals Cell-Specific Alterations in Gene Expression and Intercellular Communication
收藏Alliance of Genome Resources2026-08-01 收录
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To identify novel, cell-specific, pathological pathways that mediate heart dysfunction in Barth Syndrome, we performed single-nucleus RNA-sequencing (snRNA-seq) on wild type and Tafazzin-knockout mouse hearts. Four wild type and four Tafazzin-knockout mouse hearts were sampled to analyze using snRNA-seq.
