Here, we show that the histone H3 lysine (H3K4) methyltransferase MLL4 (a COMPASS/SET1-like enzyme; also called KMT2D) is ranked the most highly inactivated epigenetic modifier in NSCLC tumors lung-sp

NIAID Data Ecosystem40

DataSheet_1_A Genome-Wide Investigation of Effects of Aberrant DNA Methylation on the Usage of Alternative Promoters in Hepatocellular Carcinoma.zip

肝细胞癌诊断标志物

甲基化调控基因

BackgroundThe alternative usage of promoters provides a way to regulate gene expression, has a significant influence on the transcriptome, and contributes to the cellular transformation of cancer. How

NIAID Data Ecosystem30

Analysis of normal lung cells treated with 5-aza-dC to induce DNA demethylation

小细胞肺癌表观遗传学

DNA去甲基化基因表达

Analysis of 2 cultured normal lung cell lines, Normal Human Bronchial Epithelial (NHBE) and Human Small Airway Epithelial (SAEC) cells (Lonza, Walkersville, MD), following treatment with 5-aza-dC to i

NIAID Data Ecosystem60

Over-expression of DNA methyltransferase MET1 in Arabidopsis generates new epi-alleles with heritable expression states. Arabidopsis thaliana

表观等位基因

甲基化调控基因

Epigenetic marks such as DNA methylation and histone modification can vary among plant accessions creating epi-alleles with different levels of expression competence. For some genetic loci, epigenetic

NIAID Data Ecosystem30

Analysis of normal lung cells treated with 5-aza-dC to induce DNA demethylation

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