Neurotoxic pesticides: Cyfluthrin (CYF), βCYF, endosulfan (ENDO) and chlorpyrifos-oxon (CPFO) were examined using new approach methodologies (NAM) to assess ToxCast in vitro neurotoxic assay ac
Exposure to polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) has been implicated in neurodevelopmental disorders. However, the distribution of PCBs and OH-PCBs in the huma
Abstract Ammonia is involved in the pathogenesis of neurological conditions associated with hyperammonemia, including hepatic encephalopathy. Few is known about the effects of gestational exposition t
This document is intended to provide guidance on strategies and methods for testing of chemicals for potential neurotoxicity. The primary objective of this guidance is to ensure that necessary and suf
Organisation for Economic Co-operation and Development80
The fish embryo toxicity test has been proposed as an alternative for the acute fish toxicity test, but concerns have been raised for its predictivity given that a few compounds have been shown to exh