A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

NCATS Open Data2022-06-10 更新2026-08-08 收录

药物重定位

COVID-19抗病毒研究

数据链接：

https://doi.org/10.1021/acsinfecdis.2c00172 数据链接链接失效反馈

官方服务：

资源简介：

A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

创建时间：

2022-06-01

Results of the GUILDify v2.0 web server analysis.

药物重定位

病毒-宿主相互作用

Sheet (a) summarizes the overlap between the top-scoring proteins associated with the drugs and the top-scoring proteins associated with SARS-CoV-2 infection sets. Sheet (b) contains figures that illu

NIAID Data Ecosystem90

Targeting Staphylococcal Cell–Wall Biosynthesis Protein FemX Through Steered Molecular Dynamics and Drug-Repurposing Approach

药物重定位

抗金黄色葡萄球菌药物发现

Staphylococcus aureus-mediated infection is a serious threat in this antimicrobial-resistant world. S. aureus has become a “superbug” by challenging conventional as well as modern treatment strategies

NIAID Data Ecosystem90

Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2 (RNA-Seq). Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2 (RNA-Seq)

结直肠癌转移机制

药物重定位

Background Glucocorticoids (GCs), commonly used for anti-inflammatory and cancer treatments, have been linked to the promotion of cancer metastasis. Yet, the molecular mechanisms behind this potential

NIAID Data Ecosystem50

Additional file 5 of QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics

药物重定位

基因表达分析

Spreadsheet file with full details of, a) differential expression analysis results for GSE26049, b) list of probes used in the signature, and c) full results from QUADrATiC. (XLSX 5457.92 kb)

NIAID Data Ecosystem90

An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations

药物重定位

疾病关联分析

Drug development is both increasing in cost whilst decreasing in productivity. There is a general acceptance that the current paradigm of R&D needs to change. One alternative approach is drug repositi

NIAID Data Ecosystem80

A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

资源简介：

相关数据集