GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666 Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R)-3-cyclopropyl-3-[(2R)-2-(1-{(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl}piperidin-4-yl)-3,4-dihydro-2H-1-benzopyran-7-yl]-2-methylpropanoic acid, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, ... Authors: Lu, J, Byrne, N, Patel, S, Sharma, S, Soisson, S.M. Deposit date: 2016-11-22 Release date: 2017-06-07 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.22 Å) Cite: Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nat. Struct. Mol. Biol., 24, 2017
创建时间：
2016-11-22
