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Effect of intrauterine MGO administration on bovine endometrium

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE165039
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To clarify the effect of intrauterine methylglyoxal (MGO) administration on the endometrium, mRNA expression profiles of bovine endometrium were investigated. Hierarchical cluster analysis with the expression levels of all genes was divided these cows into two clusters. First cluster was composed of control cows, second cluster contained MGO (5 mM) treated cows. The day of standing estrous was defined as day 0. In cows, each uterine horn was injected with 25 mL of methylglyoxal (MGO; 0 and 5 mM) on day 1. Then, endometrial tissue from the uterine horn, ipsilateral to the CL, was biopsied on day 7. Using biopsy samples, the mRNA expression profiles of bovine endometrium were investigated to clarify the effect of intrauterine MGO administration on the endometrium.
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2021-01-22
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