Hazard ratios for cardiovascular and all-cause mortality of the logarithmically transformed Prx4.

Comparison of predictive capability of models for mortality risk prediction as determined by the Harrell’s C statistic, the IDI, and NRI.Abbreviations: Prx4, peroxiredoxin 4; HR, hazard ratio; CI, confidence interval; IDI, integrated discrimination improvement; NRI, net reclassification improvement; NA, not applicable.Cox regression models: Model 1: crude model with Prx4; Model 2: adjusted for age and gender; Model 3: adjusted for age, gender, smoking (dichotomous), body mass index, systolic blood pressure, duration of diabetes, serum creatinine level, cholesterol-HDL ratio, macrovascular complications (dichotomous), albuminuria (dichotomous); Model 4: all selected confounders without Prx4.