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Transcriptional profiling of mouse proximal tubular epithelial cells during injury and repair

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DataCite Commons2020-07-29 更新2024-07-13 收录
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https://www.rebuildingakidney.org/chaise/record/#2/Common:Collection/RID=16-E1GE
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资源简介:
We used Translating Ribosome Affinity Purification coupled with next generation sequencing (TRAP-seq) to profile mouse tubular epithelial cells during the course of injury and repair using the Kim-GCE mouse model. This novel mouse model allows lineage tracing of injured mouse tubular epithelial cells, which upregulate Kim1, and translational profiling by ribosomal pull down when crossed to the EGFP-L10a mouse. Transcriptional profiling was done at day 2, 7, and 14 after bilateral ischemia reperfusion injury.
提供机构:
(Re)building a Kidney (www.rebuildingakidney.org)
创建时间:
2019-06-10
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