Supplementary tables: An impact evaluation of two modes of care for sickle cell disease crises

These are peer-reviewed supplementary materials for the article 'An impact evaluation of two modes of care for sickle cell disease crises' published in the Journal of Comparative Effectiveness Research.Table A1: Parameters used in the model of two modes of sickle cell diseases crises careAim: To estimate the economic impacts of increased use of specialty care infusion centers for treating adults experiencing vaso-occlusive crises. Methods: A Markov model is developed to estimate the impact of expanding use of specialty care infusion centers to treat vaso-occlusive crises compared to emergency department care. Results: Access to infusion centers for sickle cell disease could result in savings over US$1.9 billion in formal medical costs and over US$2 billion in societal costs, based on uptake assumptions over 10 years. Conclusion: Expansion of adult sickle cell disease centers across the nation could lead to considerably better economic outcomes in the form of reduced costs and hospital length of stay in addition to improved clinical outcomes as reported in the existing literature.

本数据集为发表于《比较效果研究杂志》的论文《两种治疗镰状细胞病危机模式的冲击评估》的同行评审补充材料。表A1：两种镰状细胞病危机护理模式模型中使用的参数目标：估算增加使用专科护理输液中心治疗成人血管闭塞性危机的经济影响。方法：开发了一个马尔可夫模型，以估算扩大专科护理输液中心的使用范围来治疗血管闭塞性危机与急诊室护理相比的影响。结果：基于10年的采用假设，镰状细胞病患者的输液中心访问可能带来超过19亿美元的正式医疗成本节约和超过20亿美元的社会成本节约。结论：在全国范围内扩大成人镰状细胞病中心，有望显著改善经济成果，包括降低成本、缩短住院时间以及临床结果，后者如现有文献所述。