Predicted CVD genes.

The first two columns: predicted CVD genes (Entrez Gene IDs and Official Gene Symbols respectively). The third column: GO terms that the genes are annotated with. We only take into consideration GO terms in which this set of 17 genes is statistically significantly enriched. We only list GO terms that correspond to biological functions that the three drug mechanisms of interest rely on. BP denotes “biological process,” while MF denotes “molecular function” of GO. The fourth column: if we validate that the predicted gene is associated with a CVD, we give the PubMed ID of the corresponding reference; “–”means that we found no literature validation.