RNA-Seq Data and Expression Matrices for Brain and Liver from Mice Mutation Accumulation and Control Lines

A mutation accumulation (MA) study was performed on C3H/HeNRj mice for 15-19 generations. At the end of the experiment, brain and liver tissue were extracted from 200 mice from 20 MA lines, and RNA was extracted from each tissue sample, with sequencing performed to achieve an expected coverage of over 40 million paired-end reads per sample. Additionally, control lines derived from cryopreserved embryos were maintained in parallel to the sequenced MA samples, and 100 mice from 10 control lines were sequenced. See López-Cortegano et al. (in prep) for details.