Database of Genomic Variants

The objective of the Database of Genomic Variants is to provide a comprehensive summary of structural variation in the human genome. We define structural variation as genomic alterations that involve segments of DNA that are larger than 1kb. Now we also annotate InDels in 100bp-1kb range. The content of the database is only representing structural variation identified in healthy control samples. The Database of Genomic Variants provides a useful catalog of control data for studies aiming to correlate genomic variation with phenotypic data. The database is continuously updated with new data from peer reviewed research studies. We always welcome suggestions and comments regarding the database from the research community.

《基因组变异数据库》旨在提供人类基因组结构变异的全面概述。我们界定结构变异为涉及大于1kb DNA片段的基因组改变。目前，我们亦对100bp至1kb范围内的插入和缺失（InDels）进行注释。数据库内容仅代表在健康对照组中识别的结构变异。基因组变异数据库为旨在关联基因组变异与表型数据的各项研究提供了有价值的对照数据目录。数据库持续更新，以纳入经同行评审的研究的新数据。我们始终欢迎来自研究界对数据库的建议和反馈。

搜集汇总

背景与挑战

背景概述

Database of Genomic Variants (DGV) 是一个专注于人类基因组结构变异的精选数据库，主要收录大于1kb的基因组变异和100bp-1kb范围内的InDel，所有数据均来自健康对照样本，为基因组变异研究提供重要参考数据。该数据库持续更新，并与DGVa和dbVAR等数据库保持同步。