Expression data from Escherichia coli after treatment with nalidixic acid (NA). Escherichia coli

Having found that LexA degradation was significantly higher under apoptotic like death (ALD) than under SOS conditions, we hypothesized that additional genes tightly regulated by LexA would be transcribed under ALD conditions. Overall design: We used microarray analysis to test the transcription pattern of up-regulated genes in ALD. We added no NA (n.t.), 100 µg/ml NA, or 10 µg/ml NA to cultures of the WT MC4100relA+, or its ΔmazEF or ΔmazEFlexA3 derivatives.