HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound
收藏Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3lox
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HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound Descriptor: (1R,2S,5S)-N-[(2S,3R)-4-amino-1-cyclobutyl-3-hydroxy-4-oxobutan-2-yl]-6,6-dimethyl-3-{3-methyl-N-[(1-methylcyclohexyl)c arbamoyl]-L-valyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide, BETA-MERCAPTOETHANOL, HCV NS3 Protease, ... Authors: Prongay, A.J. Deposit date: 2010-02-04 Release date: 2011-02-23 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.65 Å) Cite: The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor. Bioorg.Med.Chem.Lett., 20, 2010
创建时间：
2010-02-04
