METHODS AND ANALYSIS OF SYNTHESIS OF NEW BIOLOGICALLY ACTIVE SUBSTANCES BASED ON GOSSYPOL

This article is devoted to the synthesis of new biologically active substances based on gossypol and methods for their analysis. Gossypol is a polyphenol compound found in the seeds, root bark and other parts of the cotton plant, which has a complex chemical structure and a wide spectrum of biological activity. The article discusses the chemical structure, physicochemical properties of gossypol, methods for synthesizing various derivatives based on it, and modern instrumental methods for analyzing these compounds (HPLC, GC, DART-HRMS, UPLC-MS/MS). The biological activity of gossypol derivatives and their prospects for application in medicine, veterinary medicine and agriculture are also analyzed.