Effect of rhGH on hematopoiesis.
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https://figshare.com/articles/dataset/_Effect_of_rhGH_on_hematopoiesis_/515957
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BALB/c mice were irradiated with 7.5 Gy and treated with rhGH for 5 days. Mice were sacrificed and bone marrow was harvested at day +14 post irradiation. Frequencies of CD150+CD48−CD244− and KSL cells were determined by flow cytometry. CFUs were determined after 12 days in culture. Each group contains 4–10 animals. This is a representative of three similar experiments. rhGH stands for recombinant human growth hormone; KSL cells, cells expressing c-Kit+Sca-1+Linage−/low phenotype; CFU-GM, colony forming unit-granulocyte & monocyte; BFU-E, burst forming unit-erythrocyte; CFU-GEMM, colony forming unit-granulocyte, erythrocyte, monocyte, and megakaryocyte.
aP<0.05, saline control vs. rhGH;
bP<0.05,. rhGH vs. normal BALB/c.
创建时间:
2010-06-16



