肝基质细胞限制巨噬细胞成熟，基质IL-6限制肝硬化相关巨噬细胞的分化
收藏干细胞与再生医学数据中心2023-02-10 更新2024-03-06 收录
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资源简介：
Liver disease is the cause of approximately two million deaths globally per year, yet effective therapies are lacking. Iterative tissue injury leads to prolonged inflammation, extensive fibrosis, and the possible progression to deadly chronic-end stage disease, such as cirrhosis and hepatocellular carcinoma (HCC). In this study we investigated the ability of liver stromal cells to effect macrophage maturation and differentiation by using an in vitro human stromal-myeloid coculture systems and single cell RNA sequencing.
创建时间：
2023-02-10
