The Parkinson's disease associated mutation LRRK2-G2019S affects astrocyte specification
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https://www.ncbi.nlm.nih.gov/sra/SRP213209
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资源简介：
We report the altered transcriptomic profile of astrocytes in midbrain organoids differentiated for 35 and 70 days and generated from a stem cell line carrying the LRRK2-G2019S mutation compared to the isogenic pair. Overall design: Single-cell RNA-Sequencing experiments were performed on a total of 4 samples. These correspond to 2 time-points (Day 35 and 70 of dopaminergic differentiation). One isogenic pair was analysed for each time-point: LRRK2-WT and LRRK2-G2019S.
创建时间：
2020-05-05
