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Additional file 3 of Assessing the impact of maternal blood pressure during pregnancy on perinatal health: a wide-angled Mendelian randomization study

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Additional file 3. Supplementary Tables S1–S11. Table ST1–Definitions of perinatal outcomes. Table ST2–Genetic instruments for Systolic Blood Pressure in Keaton 2024 GWAS. Table ST3–Genetic instruments for Diastolic Blood Pressure in Keaton 2024 GWAS. Table ST4–Genetic instruments for Systolic Blood Pressure in Ehret 2016 GWAS (GCST006259). Table ST5–Genetic instruments for Diastolic Blood Pressure in Ehret 2016 GWAS (GCST006258). Table ST6–MR results for the genetically predicted effects of maternal blood pressure on adverse perinatal outcomes. Table ST7–Steiger directionality test for the genetically predicted effects of maternal blood pressure on adverse perinatal outcomes. Table ST8–Heterogeneity test for the genetically predicted effects of maternal blood pressure on adverse perinatal outcomes. Table ST9–MR-Egger intercept test for the genetically predicted effects of maternal blood pressure on adverse perinatal outcomes. Table ST10–Multivariable MR for the genetically predicted effects of maternal blood pressure on adverse perinatal outcomes, accounting for body mass index, height, years of education, and age at first birth. Table ST11–MR results for the genetically predicted effects of maternal blood pressure on adverse perinatal outcomes, accounting for offspring and father genotypes through weighted linear models.
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2026-01-14
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