Histopathological scoring of mouse liver after DDC-intoxication.
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Mouse liver sections were stained with H&E (Fig. 2A) and scored for hepatocyte damage characteristics by a certified pathologist (C. L.). The average score of 5 animals (4 sections each) is shown together with the significance levels respective to controls (Error bars are SD; n.s.: not significant, * pSteatosis (0: 33–60%, 3: >60% of liver parenchyma).Microvesicular steatosis (MVS; 0: none, 1: present).Inflammation (0: none, 1: 1 focus per 200× field, 2: 2–4 foci, 3: >4 foci).Hepatocyte ballooning (0: none, 1: few, 3: many).Mallory-Denk bodies (MDBs; 0: none, 1: few, 2: many).
创建时间:
2015-12-02



