Supplementary Tables from Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q

ST1 Methods for enhancer hijacking detection ST2 Ranked and scored hematopoietic enhancers (based on ChIP-seq data for H3K27ac and P300 from K562, MOLM1 and Kasumi1) ST3 Pyjacker results for the 10 AML cell lines ST4 Pyjacker results for the 120 medulloblastoma samples ST5 Cis-x results for the 120 medulloblastoma samples ST6 Summary information for the 39 ckAML patient samples ST7 SNVs detected in WGS data for the 39 ckAML samples ST8 SVs detected in WGS data for the 39 ckAML samples ST9 CNAs detected in WGS data for the 39 ckAML samples ST10 Fusion transcripts detected in RNAseq data for the 39 ckAML samples ST11 Pyjacker results for the 39 ckAML samples ST12 Primers for qRT-PCR and validation of breakpoints (hg19) ST13 Summary of the MNX1 expression screens ST14 Summary of the MNX1-expressing samples profiled with WGS ST15 Mutations detected in the MNX1-expressing samples profiled with WGS ST16 Results of the differential expression analysis (adult and pediatric AML) ST17 TADs derived from HiC data of HSPCs ST18 Samples IDs from the TARGET-AML cohort used for the RNA-seq analysis ST19 Clinical characteristics of the patient samples from which were derived the PDX ST20 Primers and conditions used for 4C ST21 Antibodies used