YY1 Interacts with G quadruplex DNA to Regulate Gene Expression
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE142075
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资源简介：
We systematically analyzed the alterations in mRNA transcriptome evoked by knockdown of YY1 with or without pyridostatin (PDS) treatment. Statistical analysis showed a strong correlation between PDS-regulated and YY1-regulated genes (Pearson r > 0.67), underscoring the role of YY1-G4 structure interaction in YY1-mediated gene regulation. Moreover, the RNA-Seq results revealed that YY1 can positively or negatively regulate the expression of genes through its interaction with G4 structures. Examination of gene expression after knockdown of YY1 with or without pyridostatin (PDS) treatment
创建时间：
2020-08-30
