Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH -703
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Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH -703 Descriptor: 3-(2,2-diphosphonoethyl)-1-dodecyl-1H-imidazol-3-ium, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... Authors: Liu, Y.L, No, J.H, Oldfield, E. Deposit date: 2011-03-29 Release date: 2012-02-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.61 Å) Cite: Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proc.Natl.Acad.Sci.USA, 109, 2012
创建时间：
2011-03-29
