Crystal Structure of SARS-CoV-2 Mpro mutant E166A with Pfizer Intravenous Inhibitor PF-00835231
收藏Protein Data Bank Japan2025-05-21 更新2026-03-21 收录
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Crystal Structure of SARS-CoV-2 Mpro mutant E166A with Pfizer Intravenous Inhibitor PF-00835231 Descriptor: 3C-like proteinase nsp5, GLYCEROL, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide Authors: Zvornicanin, S.N, Shaqra, A.M, Schiffer, C.A. Deposit date: 2024-12-03 Release date: 2025-03-19 Last modified: 2025-05-21 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50. Mbio, 16, 2025
创建时间：
2024-12-03
