Human OCI-AML3 cells: Control vs. Atg5-shRNA or NPM1-shRNA inducibly expressed. Homo sapiens

Transcriptional profiling of human OCI-AML3 cells stably expressing inducibly Atg5 shRNA or NPM1-shRNA Goal was to determine the effects of knockdown of Atg5 or NPM1 on global ES gene expression of human Leukemia OCI-AML3 cells. Overall design: Control (Dox-) vs. inducible knock down of Atg5 (Dox+) or NPM1 (Dox+) by doxycycline. Biological replicates: 3 control replicates, Atg5-shRNA 2 replicates, NPM1-shRNA 3 replicates