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A novel prostate progenitor cell expressing Krt4 is involved in castration-resistant tumor progression

ChEBI2017-08-15 更新2026-07-12 收录

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肿瘤细胞起源研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-4991 数据链接链接失效反馈

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A novel prostate progenitor cell expressing Krt4 is involved in castration-resistant tumor progression

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创建时间：

2017-08-15

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雄激素受体信号

Genomic amplification of the androgen receptor (AR) is an established mechanism of antiandrogen resistance in prostate cancer. Here we show that the magnitude of AR signaling output, independent of AR

NIAID Data Ecosystem70

RUVBL1 promotes enzalutamide resistance of prostate tumors through the PLXNA1-CRAF-MAPK pathway

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信号通路

The aim of this research was to confirm the regulatory effect of RUVBL1 on gene expression in castration resistant prostate cancer. In this research, there were six samples examined including samples

NIAID Data Ecosystem50

Glucocorticoid Receptor Confers Resistance to Anti-Androgens by Bypassing Androgen Receptor Blockade.

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糖皮质激素受体信号

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50

Drug-induced epigenomic plasticity reprograms circadian rhythm regulation to drive prostate cancer towards androgen-independence [Cell line ChIP-Seq]

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昼夜节律表观遗传调控

In prostate cancer, androgen receptor (AR)-targeting agents are very effective in various stages of the disease. However, therapy resistance inevitably occurs and little is known about how tumor cells

NIAID Data Ecosystem70

Expression data from prostate cancer cell lines C4-2B (enzalutamide sensitive) and C4-2B-MDVR (enzalutamide resistant) cells. Homo sapiens

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差异基因表达分析

Prostate cancer C4-2B cells were cultured in enzalutamide in a dose-escalation manner. After sixty passages cells were resistant to enzalutamide, with a specific sets of genes been deregulated. We per

NIAID Data Ecosystem50

A novel prostate progenitor cell expressing Krt4 is involved in castration-resistant tumor progression

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