Human CXCR5+CD45RA-CD8+ T cells subset in follicular lymphoma
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE105095
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资源简介：
We demonstrate that CXCR5+CD8+ T cells are a distinct human T-cell subset that homes to follicles and exerts strong antitumor activity compared with CXCR5-CD8+ T cells. Importantly, this subset is associated with improved outcome in follicular lymphoma patients. Total RNA from FACS-sorted CD45RA+CD8+, CXCR5-CD45RA-CD8+, and CXCR5+CD45RA-CD8+ T cells from human tonsil samples were extracted using Trizol, followed by purification using NucleoSpin RNA XS kit. Tonsils come from tonsillectomy; these patients do not have follicular lymphoma.
创建时间：
2020-09-02
