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Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

Alliance of Genome Resources2026-08-01 收录

翻译延伸动力学

核糖体图谱分析

数据链接：

https://www.yeastgenome.org/dataset/GSE58321 数据链接链接失效反馈

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During translation elongation, the ribosome ratchets along its mRNA template, incorporating each new amino acid and translocating from one codon to the next

应用场景：

核糖体图谱分析

翻译组学

A fundamental goal of genomics is to identify the complete set of expressed proteins. Automated annotation strategies rely on assumptions about protein-coding sequences (CDSs), e.g., they are conserve

NIAID Data Ecosystem70

Additional file 2 of Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP

核糖体图谱分析

海马体翻译调控

Additional file 2: Table S1. Table of GO terms enriched in Tsc2+/−/WT upregulated RNA and RPFs from Fig. 1D, E (padj < 0.05 for cellular compartment, molecular function, and biological process).

NIAID Data Ecosystem30

Ribosome profiling of Pseudomonas fluorescens SBW25 and its hfq deletion mutant.. Ribosome profiling of Pseudomonas fluorescens SBW25 and its hfq deletion mutant.

细菌翻译调控

核糖体图谱分析

Hfq is a transcriptional and translational pleiotropic regulator in several bacteria. RNA-Seq, Ribo-Seq and Proteomic analyses were carried out in the wild-type and a hfq deletion strain of Pseudomona

NIAID Data Ecosystem20

Ribosome profiling of interspecific hybrids of Saccharomyces cerevisiae and S. paradoxus.

核糖体图谱分析

等位基因特异性表达

Ribosome profiling was performed on interspecific hybrids of Saccharomyces cerevisiae and S. paradoxus in order to identify allele-specific expression indicative of cis-regulatory divergence at the le

NIAID Data Ecosystem40

Ribosome profiling data from the model diatom Thalassiosira pseudonana Part 2

核糖体图谱分析

胁迫响应

Sequencing data from ribosome profiling run described in the protocol paper 'Ribosome profiling in the model diatom Thalassiosira pseudonana' HT_4: High temperature exposure (32°C) for 4 hours HT

NIAID Data Ecosystem30

Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

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