hg38 syntenic ages
收藏NIAID Data Ecosystem2026-03-13 收录
下载链接：
https://zenodo.org/record/5809633
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资源简介：
### METHOD ###
Sequence ages were estimated from hg38 100-way multiZ vertebrate sequence alignments from the UCSC genome browser. Briefly, sequence ages were estimated as the branch length between humans (hg38) and the oldest most recent common ancestor (MRCA) from the 100-way neutral tree.
MRCA to taxon mappings are available in the hg38_syn_taxon.bed file.
# Hg38 100-way vertebrate tree syntenic block age files.
Information for hg38 100-way vertebrate multiple sequence alignment can be found here - http://hgdownload.cse.ucsc.edu/goldenPath/hg38/multiz100way/README.txt
# Scripts generating these files
(1) Creating syntenic block .bed files
https://github.com/slifong08/enh_ages/blob/54084ff12e521c20cc5288d6cb3590fac93c11ed/age_arch/manuscript_scripts/get_spec_count_msa-hg19.py
(2) Assigning most recent common ancestor (MRCA) and patristic distances to syntenic blocks
https://github.com/slifong08/enh_ages/blob/54084ff12e521c20cc5288d6cb3590fac93c11ed/age_arch/manuscript_scripts/get_synteny_age_hg19.py
创建时间：
2021-12-30
