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Human TLR4/MD-2 knockin (KI) mice and comparison of TLR4 agonists ability to enhance innate immunity and development of adaptive immunity in mice

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NIAID Data Ecosystem2026-05-10 收录
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The study's aim is to generate human TLR and MD-2 knockin (KI) mice to assess host responses to infections with Y. pestis and to evaluate the safety and efficacy of purified/synthetic TLR4 ligand immunotherapeutics.

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2025-10-30
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