Differences in outcome in patients with CNS relapse, allocated either transplantation or chemoradiotherapy according to whether they received Idarubicin or Mitoxantrone.

c-CNS = combined CNS relapse; i-CNS = isolated CNS relapse; TRM = Therapy related mortality; SCT = allogeneic transplantation; CR2 = second remission; Ida = Idarubicin; Mito = Mitoxantrone. *Patients allocated SCT were, all those with very early relapse; early i-CNS relapses and early and late c-CNS relapses with MRD ≥10−4 at the end of induction. Where MRD was not evaluable, decision to transplant was based on duration of CR1. All other patients were allocated chemoradiotherapy. Differences in outcome in patients with CNS relapse, allocated either transplantation or chemoradiotherapy according to whether they received Idarubicin or Mitoxantrone.