Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an intermediate state
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Cryo-EM structure of eSaCas9_NNG-guide RNA-target DNA complex in an intermediate state Descriptor: CRISPR-associated endonuclease Cas9, Non-target DNA strand, Target DNA strand, ... Authors: Omura, S.N, Nakagawa, R, Yamashita, K, Nishimasu, H, Nureki, O. Deposit date: 2024-04-30 Release date: 2025-11-05 Last modified: 2026-04-29 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Engineering a compact high-fidelity Staphylococcus aureus Cas9 variant with broader targeting range and mechanistic insights into its activation. Nat Commun, 17, 2026
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2024-04-30
