Aberrant RNA splicing may contribute to carcinogenesis. Here, we focused on the G96V mutation in SNRPD3, one of the splicing factors. We found that RNA splicing is altered under hypoxia in cell lines
Ser/Arg-rich proteins (SR proteins) are essential splicing factors that commit pre-messenger RNAs to splicing and also modulate 5' splice site choice in the presence or absence of functional U1 small