Reactions that were changed in the background of the G38D mutation.
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aReaction number, corresponding to that in Figure 1.bType of reaction.cOriginal value of the parameter governing the reaction kinetics in the mathematical model (s−1) [14].dMinimum and maximum reductions the considered parameters were subjected to in the present study, in order to model the mutated conditions; when “Max R” was 0, the parameter was ultimately set to zero.eEffect of these reductions.
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2015-12-02



