Successful navigation of the mouse preimplantation stages of development, during which three distinct blastocyst lineages are derived, represents a prerequisite for continued development. We previousl
Replication stress threatens genome integrity by exposing replication forks to nucleolytic degradation. In both yeast and humans, the checkpoint kinases Mec1 and Rad53 limit deleterious single-strande
Here we analyse steady state mRNA levels and yH2A-marked replication fork stalling sites in S. cerevisiae Overall design: Histone modification (yH2A, gammaH2A) and transcriptome (mRNA-Seq) from wildty
Mutations in the oligomerization domain of p53 are genetically linked to cancer susceptibility in Li-Fraumeni Syndrome. These mutations typically alter the oligomeric state of p53 and impair its trans
Larger processed svCapture data files related to the linked publication. Two types of files are provided: 1) Data packages, ending in .mdi.package.zip = processed data files that can be loaded by th