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Histidine-Catalyzed Asymmetric Aldol Addition of Enolizable Aldehydes: Insights into its Mechanism

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https://figshare.com/articles/dataset/Histidine_Catalyzed_Asymmetric_Aldol_Addition_of_Enolizable_Aldehydes_Insights_into_its_Mechanism/2544838
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资源简介:
Extensive studies of asymmetric cross-aldol addition between enolizable aldehydes are described and provide a deeper insight into histidine-catalyzed aldol additions. In particular, aspects of enantio- as well as diastereoselectivity of these reactions are discussed. Rules and predictions of configurative outcome are explained by using different transition-state models. These discussions are confirmed by extensive computations.
创建时间:
2012-03-02
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