FeCl3‑Catalyzed Four-Component Nucleophilic Addition/Intermolecular Cyclization Yielding Polysubstituted Pyridine Derivatives
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https://figshare.com/articles/dataset/FeCl_sub_3_sub_Catalyzed_Four_Component_Nucleophilic_Addition_Intermolecular_Cyclization_Yielding_Polysubstituted_Pyridine_Derivatives/2253445
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We report an efficient route to pyridine derivatives via an FeCl3-catalyzed four-component nucleophilic addition/intermolecular cyclization. This simple fragment assembly strategy uses mild conditions and affords a broad range of polysubstituted pyridines in moderate to good yield from simple and readily available starting materials. A plausible mechanism for this process is proposed.
创建时间:
2016-02-16



