Background Botulism is a disease caused by neurogenic toxins that block acetylcholine release, resulting in potentially life threatening neuroparalysis. Seven distinct serotypes of botulinum neurotoxi
An in vivo experiment to understand the impact of PHD inhibition on SARS-CoV-2 infection. Hamsters infected with SARS-CoV-2 received pre- or post-infection doses of the PHD inhibitor FG-4592.
Nipah virus (NiV) is a highly pathogenic virus associated with outbreaks in Malaysia, Bangladesh, and India with high mortality rates. NiV infection causes fatal respiratory and neurological disease.
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or the