Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy

For
the first time, enantiomerically enriched atropoisomeric furans
have been accessed using a central-to-axial chirality conversion strategy.
Hence, oxidation of the enantioenriched dihydrofuran precursors gave
rise to axially chiral furans with high enantiopurities accounting
from excellent conversion percentages (cp) in most cases.