Effect of knockdown of Secisbp2l in primary oligodendrocyte precursor cells

To investigate the function of Secibp2l which we identified as an oligodendrocyte-specific RNA binding protein, we performced transcriptome profiling of primary oligodnedrocytes with Secisbp2l knockdown by siRNA. We then performed gene expression profiling analysis using data obtained from RNA-seq. Comparative gene expression profiling analysis of RNA-seq data for mouse primary oligodendrocytes and its KD derivatives (siSbp2l, siPdgfra, siNegativeControls).