In vitro antitubercular and in vitro metabolic profile.

Structures, inhibitory activity, and in vitro PK properties of experimental and reference nitrofurans.aThe lowest concentration of drug that prevented visible growth.bCytotoxicity against Vero epithelial cells using MTT assay.cSelectivity for tuberculosis.dMaximum solubility calculated by µSol Evolution Software.eMetabolic stability performed with mouse liver microsomes.fPlasma protein binding assays performed using mouse plasma.gIndicates values reported in reference.hIndicates values reported in reference.