Investigation of differentially-expressed microRNAs involved in infected nonunion of the human long bones through microRNA expression profiling

20 miRNAs were identified as differentially expressed in patients with infected nonunion of long bones, which may facilitate the diagnosis of infected nonunion of long bones. In this study, we analyze the expression of miRNAs from bone tissues of the fractured end of the bone in five patients with infected nonunion of long bones and four patients with freshly-closed fractures in order to provide novel diagnostic tools.